Depyrogenation tunnel validation protocol

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    The Sterilizing & Depyrogenating Tunnel when operated with Empty Chamber is capable of producing the temperature profiles as per the temperature set points set
    Depyrogenation Tunnel Validation In aseptic filling units, OQ and PQ studies of tunnels used for depyrogenization process after washing of containers such asDH Depyrogenation OQ/PQ Studies for continuous belt tunnels should consist of a minimum of three (3) consecutive, successful runs based on a matrix approach
    and the various tests performed for the qualification of Depyrogenation Tunnels. Key words: Depyrogenation, Bacterial Endotoxin, Performance Qualification.

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